2414056-35-0

HER2-IN-14 Chemical Structure
2414056-35-0

Chemical Structure

HER2-IN-14

  • CAS No.: 2414056-35-0
  • Formula:C26H23ClF2N8O3
  • Molecular Weight:568.96

IUPAC Name: (S)-N-(4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)-3-chlorophenyl)-5-((3,3-difluoro-1-methylpiperidin-4-yl)oxy)-6-methoxyquinazolin-4-amine

InChIKey: OCTIIGKPLDEYJH-FQEVSTJZSA-N

SMILES: ClC(C=C1NC2=NC=NC3=C2C(O[C@@H]4C(F)(CN(CC4)C)F)=C(OC)C=C3)=C(C=C1)OC5=CC6=NC=NN6C=N5

Biological Activity: HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-153557A 		HER2-IN-14 HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM.
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