2414056-34-9
2414056-34-9
Chemical Structure
HER2-IN-13
- CAS No.: 2414056-34-9
- Formula:C26H23ClF2N8O3
- Molecular Weight:568.96
IUPAC Name: (R)-N-(4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)-3-chlorophenyl)-5-((3,3-difluoro-1-methylpiperidin-4-yl)oxy)-6-methoxyquinazolin-4-amine
InChIKey: OCTIIGKPLDEYJH-HXUWFJFHSA-N
SMILES: ClC(C=C1NC2=NC=NC3=C2C(O[C@H]4C(F)(CN(CC4)C)F)=C(OC)C=C3)=C(C=C1)OC5=CC6=NC=NN6C=N5
Biological Activity: HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HER2-IN-13 | HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM. | |||||||||||||||||||||
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References
Keywords
