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Cat. No.: HY-146674

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IDO1/TDO-IN-3

IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC₅₀: 0.005 μM) and TDO (IC₅₀: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed.

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CAS No.: 2347579-03-5
Formule: C₁₆H₆ClF₂N₃O₂
Masse moléculaire:345.69

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

IDO1/TDO-IN-3 Chemical Structure

CAS No.: 2347579-03-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Voir tous les produits spécifiques à Isoform Indoleamine 2,3-Dioxygenase (IDO) :

Chemical Information

CAS No. 2347579-03-5
Masse moléculaire 345.69
Formule C₁₆H₆ClF₂N₃O₂
SMILES

O=C1C2=CC(F)=CC=C2C(C3=C1N=NN3C4=CC=C(C(Cl)=C4)F)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO). Eur J Med Chem. 202 [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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IDO1/TDO-IN-3

Voir tous les produits spécifiques à Isoform Indoleamine 2,3-Dioxygenase (IDO)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

IDO1/TDO-IN-3 Related Classifications

HY-146674 Related Classifications