2347579-03-5
2347579-03-5
Chemical Structure
IDO1/TDO-IN-3
- CAS No.: 2347579-03-5
- Formula:C16H6ClF2N3O2
- Molecular Weight:345.69
IUPAC Name: 1-(3-chloro-4-fluorophenyl)-6-fluoro-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione
InChIKey: KGLAAILBKHAJFQ-UHFFFAOYSA-N
SMILES: O=C1C2=CC(F)=CC=C2C(C3=C1N=NN3C4=CC=C(C(Cl)=C4)F)=O
Biological Activity: IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed[1].
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IDO1/TDO-IN-3 | IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed. | |||||||||||||||||||||
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References
Keywords
