IDO1/TDO-IN-3
IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed.
For research use only. We do not sell to patients.
- CAS No.: 2347579-03-5
- Formula: C16H6ClF2N3O2
- Molecular Weight:345.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2347579-03-5
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Molecular Weight 345.69
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Formula C16H6ClF2N3O2
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SMILES
O=C1C2=CC(F)=CC=C2C(C3=C1N=NN3C4=CC=C(C(Cl)=C4)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1/TDO-IN-3 Related Classifications
HY-146674 Related Classifications
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