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Cat. No.: HY-50898S5

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Lapatinib-¹³C,d₇

(Synonyms: GW572016-¹³C,d₇; GW2016-¹³C,d₇)

Lapatinib-¹³C,d₇ (GW572016-¹³C,d₇) is the deuterium and ¹³C-labeled Lapatinib (HY-50898). Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

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CAS No.: 1210608-87-9
Formule: C₂₈¹³CH₁₉D₇ClFN₄O₄S
Masse moléculaire:589.09

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lapatinib-¹³C,d₇ Chemical Structure

CAS No.: 1210608-87-9

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Activité biologique

Description

Voir tous les produits spécifiques à Isoform EGFR :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1210608-87-9
Unlabeled Cas 231277-92-2
Masse moléculaire 589.09
Formule C₂₈¹³CH₁₉D₇ClFN₄O₄S
SMILES

[2H][13C]([2H])([2H])S(C([2H])([2H])C([2H])([2H])NCC1=CC=C(O1)C2=CC(C(NC3=CC(Cl)=C(C=C3)OCC4=CC(F)=CC=C4)=NC=N5)=C5C=C2)(=O)=O
Synonyms

GW572016-¹³C,d₇; GW2016-¹³C,d₇
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.