Lepunafusp alfa
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2396411-71-3
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
fused with Homo sapiens IDUA (iduronidase, alpha-L-) isoform 1, Pr27-653 (1:2)
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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F(ab')2-G1-kappa
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2396411-71-3
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SMILES
[Lepunafusp alfa]
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Synonyms
JR-171
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)