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Cat. No.: HY-18593

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Mal-β-CD

(Synonyms: 6-O-alpha-D-Maltosyl-beta-cyclodextrin)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

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Pureté: 99.91%
CAS No.: 104723-60-6
Formule: C₅₄H₉₀O₄₅
Masse moléculaire:1459.27

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mal-β-CD Chemical Structure

CAS No.: 104723-60-6

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Activité biologique
- Description
- In Vitro
Chemical Information
Publications (2)
Solvant et solubilité
- In Vitro
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

In Vitro

Mal-β-CD removes cellular cholesterol forming inclusion complexes, while Mal-β-CD-induced lack of cellular cholesterol is replenished by the addition of cholesterol/Mal-β-CD inclusion complex (CLM) without cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 104723-60-6
Appearance Solid
Masse moléculaire 1459.27
Formule C₅₄H₉₀O₄₅
Color White to off-white
SMILES

O[C@@H]1[C@@H](CO)O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](OC[C@H]3O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O6)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]3O[C@H]7O[C@H](CO)[C@@H](O[C@@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]9[C@H](O)[C@@H](O)[C@H](OC%10[C@H](O)[C@@H](O)[C@H]6[C@@H](CO)O%10)[C@@H](CO)O9)[C@@H](CO)O8)[C@H](O)[C@H]7O)O[C@@H]2CO)[C@H](O)[C@H]1O
Synonyms

6-O-alpha-D-Maltosyl-beta-cyclodextrin
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Biochem Biophys Res Commun

Avapritinib efficacy in primary hepatic neuroendocrine carcinoma with elevated PDGFRA expression: Insights from a PDX model study. [Abstract]

2024 Aug 6:736:150504. PMID: 39121673
Biosci Biotechnol Biochem

Solubilization and stabilization of lipoic acid trisulfide by creation of various β-cyclodextrin clathrates. [Abstract]

2024 May 22;88(6):601-607. PMID: 38569654

Solvant et solubilité

In Vitro:

DMSO : ≥ 100 mg/mL (68.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : ≥ 60.5 mg/mL (41.46 mM)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact

MedChemExpress (MCE) .

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (286 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
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OR (2659 KB)
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Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Okada Y, et al. Effect of 6-O-α-maltosyl-β cyclodextrin and its cholesterol inclusion complex on cellular cholesterol levels and ABCA1 and ABCG1 expression in mouse mastocytoma P-815 cells. Carbohydr Res. 2012 Aug 1;357:68-74. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O / DMSO	1 mM	0.6853 mL	3.4264 mL	6.8527 mL	17.1319 mL
	5 mM	0.1371 mL	0.6853 mL	1.3705 mL	3.4264 mL
	10 mM	0.0685 mL	0.3426 mL	0.6853 mL	1.7132 mL
	15 mM	0.0457 mL	0.2284 mL	0.4568 mL	1.1421 mL
	20 mM	0.0343 mL	0.1713 mL	0.3426 mL	0.8566 mL
	25 mM	0.0274 mL	0.1371 mL	0.2741 mL	0.6853 mL
	30 mM	0.0228 mL	0.1142 mL	0.2284 mL	0.5711 mL
	40 mM	0.0171 mL	0.0857 mL	0.1713 mL	0.4283 mL
DMSO	50 mM	0.0137 mL	0.0685 mL	0.1371 mL	0.3426 mL
DMSO	60 mM	0.0114 mL	0.0571 mL	0.1142 mL	0.2855 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Keywords

Mal-β-CD

2 Cited Publications

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Activité biologique
- Description
- In Vitro
Chemical Information
Publications (2)
Solvant et solubilité
- In Vitro
Pureté et documentation
Références

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Mal-β-CD

Publications Citing Use of MedChemExpress (MCE) Mal-β-CD

Activité biologique

Chemical Information

Publications (2)

Solvant et solubilité

Pureté et documentation

Références

Calculators

Help & FAQs

Complete Stock Solution Preparation Table

Mal-β-CD Related Classifications

HY-18593 Related Classifications