[Effect of riodoxol on herpes simplex virus morphogenesis in experimental eye infection]

  • Vopr Virusol. 1982 Jan-Feb;(1):90-4.
L F Stebaeva ,  I S Nikolaeva ,  G N Pershin
PMID: 6280397
Abstract

The effect of riodoxol on herpes simplex type 1 viruses was studied. It was shown to affect multiplication and maturation of the virus as manifested in the appearance of virions with incomplete nucleoid structure and long-term presence of virions in cytoplasmic vacuoles in cells. Submicroscopic changes suggest a dual effect of riodoxol on herpes simplex virus: on the DNA replicative cycle and on the stage of late maturation of virus at the time of its release from the nucleus.'

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