SDX-7539
SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2). SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice.
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- CAS No.: 1631953-52-0
- Formule: C23H38N2O5
- Masse moléculaire:422.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:A549 xenograft athymic nude mice[1]
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Dosage:37 mg/kg
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Administration:i.v., every two days for 20 days
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Result:Inhibited tumor growth.
Chemical Information
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CAS No. 1631953-52-0
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Masse moléculaire 422.56
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Formule C23H38N2O5
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SMILES
[H][C@@]1([C@@H]([C@@H](CC[C@@]12OC2)OC(N[C@@H]3CC[C@@H](N)CC3)=O)OC)[C@]4(O[C@@H]4C/C=C(C)\C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)