1631953-52-0
1631953-52-0
Chemical Structure
SDX-7539
- CAS No.: 1631953-52-0
- Formula:C23H38N2O5
- Molecular Weight:422.56
InChIKey: NRQIOBIGZOJSBU-GBRHDRKCSA-N
SMILES: [H][C@@]1([C@@H]([C@@H](CC[C@@]12OC2)OC(N[C@@H]3CC[C@@H](N)CC3)=O)OC)[C@]4(O[C@@H]4C/C=C(C)\C)C
Biological Activity: SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2). SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice[1].
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SDX-7539 | SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2). SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice. | |||||||||||||||||||||
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