SDX-7539
SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2). SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice.
For research use only. We do not sell to patients.
- CAS No.: 1631953-52-0
- Formula: C23H38N2O5
- Molecular Weight:422.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:A549 xenograft athymic nude mice[1]
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Dosage:37 mg/kg
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Administration:i.v., every two days for 20 days
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Result:Inhibited tumor growth.
Chemical Information
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CAS No. 1631953-52-0
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Molecular Weight 422.56
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Formula C23H38N2O5
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SMILES
[H][C@@]1([C@@H]([C@@H](CC[C@@]12OC2)OC(N[C@@H]3CC[C@@H](N)CC3)=O)OC)[C@]4(O[C@@H]4C/C=C(C)\C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDX-7539 Related Classifications
HY-158006 Related Classifications
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