SDZ-FOX-988
SDZ-FOX-988 (FOX-988) is an orally active antidiabetic agent. SDZ-FOX-988 sequesters mitochondrial coenzyme A to inhibit carnitine palmitoyltransferase II. SDZ-FOX-988 induces mitochondrial injury. SDZ-FOX-988 causes a decrease in serum β-hydroxybutyrate or glucose. SDZ-FOX-988 can be used in the research of type 2 diabetes.
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- CAS No.: 139681-18-8
- Formule: C25H29NO5
- Masse moléculaire:423.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 139681-18-8
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Masse moléculaire 423.50
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Formule C25H29NO5
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SMILES
O=C(C(C)(C)C)C1=CC=C(/C(OC(C2=CC=C(C(C(C)(C)C)=O)C=C2)=O)=N\OC)C=C1
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Synonyms
FOX-988
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Lau DT, et al. The effect of the fat content of food on the pharmacokinetics and pharmacodynamics of SDZ FOX 988, an antidiabetic agent, in the dog. Biopharm Drug Dispos. 1995 Mar;16(2):137-50. [Content Brief]
[2]. Vickers AE, et al. Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices. Toxicol In Vitro. 2006 Oct;20(7):1173-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDZ-FOX-988 Related Classifications
HY-19150 Related Classifications
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