TrmD-IN-1
TrmD-IN-1 (compound 8h) is a selective Staphylococcus aureus tRNA m1 G37 methyltransferase (TrmD) inhibitor with a KD of 2.48 μM and an IC50 of 1.16 μM. TrmD-IN-1 exhibits selectivity over E. coli (KD > 30 μM) and H. influenzae TrmD (KD > 30 μM) and Trm5 (IC50 > 30 μM).
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- Formule: C11H13N9O
- Masse moléculaire:287.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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S. aureus TrmD 1.16 μM (IC50) |
S. aureus TrmD 2.48 μM (Kd) |
E. coli TrmD >30 μM (Kd) |
H. influenzae TrmD >30 μM (Kd) |
Trm5 >30 μM (IC50) |
Chemical Information
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Masse moléculaire 287.28
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Formule C11H13N9O
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SMILES
O=C1NC=NC2=C1C(C3=CN(N=N3)CCNC(N)=N)=CN2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TrmD-IN-1 Related Classifications
HY-180544 Related Classifications
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