1259296-46-2
Chemical Structure
MPI_5a
- CAS No.: 1259296-46-2
- Formula:C16H17N3O3
- Molecular Weight:299.32
IUPAC Name: N-hydroxy-2-(1-methyl-1H-pyrrole-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
InChIKey: NNQAQGDSGCGFER-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(CN(C(C3=CC=CN3C)=O)CC2)C=C1)NO
Biological Activity: MPI_5a is a potent and selective HDAC6 inhibitor (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms. MPI_5a inhibits acyl-tubulin accumulation in cells with an IC50 value of 210 nM[1].
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MPI_5a | 99.0% | MPI_5a is a potent and selective HDAC6 inhibitor (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms. MPI_5a inhibits acyl-tubulin accumulation in cells with an IC50 value of 210 nM. | ||||||||||||||||||||
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Keywords