1356340-69-6
Chemical Structure
Anticancer agent 236
- CAS No.: 1356340-69-6
- Formula:C27H17F2N3O6
- Molecular Weight:517.44
IUPAC Name: (R)-9-acetyl-1'-allyl-2,7'-difluoro-10-methyl-6H-spiro[chromeno[3',4':5,6]pyrano[2,3-d]pyrimidine-7,3'-indoline]-2',6,8(9H)-trione
InChIKey: WVKHBHOIOXXGLG-MHZLTWQESA-N
SMILES: O=C(N(C1=C2C=CC=C1F)CC=C)[C@@]32C4=C(OC(N=C(N5C(C)=O)C)=C3C5=O)C6=CC(F)=CC=C6OC4=O
Biological Activity: Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC50 values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ)[1].
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Anticancer agent 236 | Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC50 values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ). | |||||||||||||||||||||
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Keywords
