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Cat. No.: HY-117782

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Anticancer agent 236

Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC₅₀ values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ).

For research use only. We do not sell to patients.

CAS No.: 1356340-69-6
Formula: C₂₇H₁₇F₂N₃O₆
Molecular Weight:517.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Anticancer agent 236 Chemical Structure

CAS No.: 1356340-69-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1356340-69-6
Molecular Weight 517.44
Formula C₂₇H₁₇F₂N₃O₆
SMILES

O=C(N(C1=C2C=CC=C1F)CC=C)[C@@]32C4=C(OC(N=C(N5C(C)=O)C)=C3C5=O)C6=CC(F)=CC=C6OC4=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiang X, et al. Core scaffold‐inspired concise synthesis of chiral spirooxindole‐pyranopyrimidines with broad‐spectrum anticancer potency[J]. Advanced Synthesis & Catalysis, 2012, 354(5): 917-925.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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