136675-87-1
136675-87-1
Chemical Structure
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine
- CAS No.: 136675-87-1
- Formula:C23H19FN2O6
- Molecular Weight:438.41
IUPAC Name: ((2R,3R,4S,5R)-3-(benzoyloxy)-4-fluoro-5-(2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate
InChIKey: NNEJQWKQUWJJSO-IYWMVGAKSA-N
SMILES: F[C@H]1[C@H](OC(C2=CC=CC=C2)=O)[C@@H](COC(C3=CC=CC=C3)=O)O[C@H]1N4C(N=CC=C4)=O
Biological Activity: 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine | 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
