1370281-06-3
Chemical Structure
(E)-FOBISIN101
- CAS No.: 1370281-06-3
- Formula:C15H11N3Na3O8P
- Molecular Weight:461.21
IUPAC Name: trisodium mono((E)-4-((4-formyl-5-hydroxy-6-methyl-3-((phosphonooxy)methyl)pyridin-2-yl)diazenyl)benzoate)
InChIKey: VCUDBCPCDKEAKO-GLCFPVLVSA-K
SMILES: O=C(O[Na])C(C=C1)=CC=C1/N=N/C2=C(COP(O[Na])(O[Na])=O)C(C=O)=C(C(C)=N2)O
Biological Activity:
(E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E)-FOBISIN101 | 95.63% | (E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research. |
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Keywords
