150527-23-4
150527-23-4
Chemical Structure
FG-5893
- CAS No.: 150527-23-4
- Formula:C27H29F2N3O2
- Molecular Weight:465.53
IUPAC Name: methyl 2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)nicotinate
InChIKey: NDCPNKXUTJGQQC-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=CN=C1N2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
Biological Activity: FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect[1][2].
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FG-5893 | FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect. | |||||||||||||||||||||
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References
- [1]. Gunnar Andersson, et al. Effects of FG 5893, a new compound with 5-HT1A receptor agonistic and 5-HT2 receptor antagonistic properties, on male rat sexual behavior. European Journal of Pharmacology. Volume 255, Issues 1–3, 1 April 1994, Pages 131-137.
- [2]. Albinsson A, et al. Preclinical pharmacology of FG5893: a potential anxiolytic drug with high affinity for both 5-HT1A and 5-HT2A receptors. Eur J Pharmacol. 1994 Aug 22;261(3):285-94. [Content Brief]
Keywords
