1612192-01-4
1612192-01-4
Chemical Structure
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
- CAS No.: 1612192-01-4
- Formula:C14H12ClFN4O3S
- Molecular Weight:370.79
IUPAC Name: (2R,3S,4S,5R)-2-(2-chloro-6-(thiophen-3-yl)-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: HHDRPJYWNFGOEM-KMEHANEDSA-N
SMILES: OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C(N=C(Cl)N=C3C4=CSC=C4)=C3N=C2)O1
Biological Activity: 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside | 2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
