1628574-81-1
1628574-81-1
Chemical Structure
c-Fms-IN-6
- CAS No.: 1628574-81-1
- Formula:C22H25N7O2
- Molecular Weight:419.48
IUPAC Name: 5-(tert-butyl)-2-(5-((2-(1-ethyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)-6-methylpyridin-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
InChIKey: NWTRDIYLEGZNSX-UHFFFAOYSA-N
SMILES: O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(CC)N=C4)=NC=C3)C=C2)N=C(C(C)(C)C)N1
Biological Activity: c-Fms-IN-6 is a potent inhibitor of c-FMS, with an IC50 of ≤10 nM for unphosphorylated c-FMS, also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50, > 1 μM). Used in the research of autoimmune diseases[1].
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c-Fms-IN-6 | c-Fms-IN-6 is a potent inhibitor of c-FMS, with an IC50 of ≤10 nM for unphosphorylated c-FMS, also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50, > 1 μM). Used in the research of autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
