c-Fms-IN-6
c-Fms-IN-6 is a potent inhibitor of c-FMS, with an IC50 of ≤10 nM for unphosphorylated c-FMS, also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50, > 1 μM). Used in the research of autoimmune diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1628574-81-1
- 分子式: C22H25N7O2
- 分子量:419.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
IC50: ≤10 nM (c-FMS)[1]
体外実験
c-Fms-IN-6 (Example 38) shows inhibitory activity against M-NFS-60 cell proliferation, with an IC50 in the range of 0.01 μM to 0.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1628574-81-1
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分子量 419.48
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分子式 C22H25N7O2
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SMILES
O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(CC)N=C4)=NC=C3)C=C2)N=C(C(C)(C)C)N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)