18109-80-3
Chemical Structure
Butamirate
- CAS No.: 18109-80-3
- Formula:C18H29NO3
- Molecular Weight:307.43
IUPAC Name: 2-(2-(diethylamino)ethoxy)ethyl 2-phenylbutanoate
InChIKey: DDVUMDPCZWBYRA-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=CC=C1)CC)OCCOCCN(CC)CC
Biological Activity: Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma[1][2].
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Butamirate | 96.48% | Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma. | ||||||||||||||||||||
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- [1]. Płusa T. et al. Butamirate citrate in control of cough in respiratory tract inflammation. Pol Merkur Lekarski. 2017 Aug 21;43(254):69-74. [Content Brief]
- [2]. Lee SJ, et al. Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents. Sci Rep. 2021 May 12;11(1):10145. [Content Brief]
Keywords