185897-02-3
Chemical Structure
Indinavir-d6
Synonym(s): MK-639-d6 free base; L-735524-d6 free base
- CAS No.: 185897-02-3
- Formula:C36H41D6N5O4
- Molecular Weight:619.83
IUPAC Name: (S)-1-((2S,4R)-4-benzyl-2-hydroxy-5-(((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino)-5-oxopentyl)-N-(tert-butyl)-4-((pyridin-3-yl-d4)methyl-d2)piperazine-2-carboxamide
InChIKey: CBVCZFGXHXORBI-JYVVPHGCSA-N
SMILES: CC(C)(C)NC([C@H](CN(CC1)C([2H])([2H])C2=C([2H])N=C([2H])C([2H])=C2[2H])N1C[C@@H](O)C[C@@H](CC3=CC=CC=C3)C(N[C@H]4C5=CC=CC=C5C[C@H]4O)=O)=O
Biological Activity: Indinavir-d6 is the deuterium labeled Indinavir. Indinavir (MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indinavir-d6 | Indinavir-d6 is the deuterium labeled Indinavir. Indinavir (MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability. | |||||||||||||||||||||
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Indinavir-13C4,15N | Indinavir-13C4,15N (MK-639 (free base)-13C4,15N) is 13C and 15N labeled Indinavir. Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor. | |||||||||||||||||||||
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Indinavir | 99.96% | Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor. | ||||||||||||||||||||
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Similarity Score 1.00
HY-B0689C(threo)-Indinavir -
Similarity Score 0.92
HY-B0689BIndinavir sulfate ethanolate -
Similarity Score 0.82
HY-120812HIV-IN-11 -
Similarity Score 0.80
HY-106188L 756423 -
Similarity Score 0.62
HY-U00261L-689502 -
Similarity Score 0.51
HY-17007Saquinavir -
Similarity Score 0.50
HY-106942CGP 53437 -
Similarity Score 0.48
HY-U00362Neurodegenerative Disorder-Targeting Compound 1 -
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