1996629-79-8
1996629-79-8
Chemical Structure
TBOPP
- CAS No.: 1996629-79-8
- Formula:C24H21F3N2O4S
- Molecular Weight:490.49
IUPAC Name: 1-(2-oxo-2-(3'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)ethyl)-5-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one
InChIKey: ZMPDEBWNVHAKBB-UHFFFAOYSA-N
SMILES: O=C1C=CC(S(=O)(N2CCCC2)=O)=CN1CC(C3=CC=C(C4=CC=CC(C(F)(F)F)=C4)C=C3)=O
Biological Activity: TBOPP is a selective inhibitor of DOCK1 with an IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with high affinity (Kd of 7.1 μM), has anti-tumor activity for broader types of tumors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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TBOPP | 99.35% | TBOPP is a selective inhibitor of DOCK1 with an IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with high affinity (Kd of 7.1 μM), has anti-tumor activity for broader types of tumors. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.53
HY-16202611β-HSD1-IN-14 -
Similarity Score 0.51
HY-146811HSGN-94 -
Similarity Score 0.51
HY-171006IRF1-IN-1 -
Similarity Score 0.50
HY-174212MXC-017 -
Similarity Score 0.50
HY-130836LpxH-IN-AZ1 -
Similarity Score 0.49
HY-128026MMP-9/MMP-13 Inhibitor I -
Similarity Score 0.49
HY-106447Losulazine -
Similarity Score 0.49
HY-183779Antiangiogenic agent 10 -
Similarity Score 0.49
HY-157179WAY-312491 -
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