2134675-36-6

Ziftomenib Chemical Structure
2134675-36-6

Chemical Structure

Ziftomenib

Synonym(s): KO-539

  • CAS No.: 2134675-36-6
  • Formula:C33H42F3N9O2S2
  • Molecular Weight:717.87

IUPAC Name: (S)-4-methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

InChIKey: BGGALFIXXQOTPY-NRFANRHFSA-N

SMILES: N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)(F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Biological Activity: Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities (WO2017161028A1, compound 151)[1].

Cat. No. Product Name Purity Description Pricing
HY-132001
Ziftomenib 99.43% Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities (WO2017161028A1, compound 151).
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HY-132001S
Ziftomenib-d3 Ziftomenib-d3 (KO-539-d3) is the deuterium labeled Ziftomenib (HY-132001). Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities.
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References