2796195-48-5
2796195-48-5
Chemical Structure
SPH7854
- CAS No.: 2796195-48-5
- Formula:C24H25N3O4S
- Molecular Weight:451.54
InChIKey: IMKXQRYNCDBQIW-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(C(C2=NC=CC=C2)(C)C)=O)N=C1)CC3=CC=C(S(=O)(CC)=O)C=C3
Biological Activity: SPH7854 is a RORγt inhibitor with human RORγt IC50 of 10 nM, high selectivity over RORα and RORβ, and oral effectiveness. SPH7854 suppresses RORγt activity, Th17 cell differentiation, and IL-17 production. SPH7854 can be used for the research of inflammatory bowel disease[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SPH7854 | SPH7854 is a RORγt inhibitor with human RORγt IC50 of 10 nM, high selectivity over RORα and RORβ, and oral effectiveness. SPH7854 suppresses RORγt activity, Th17 cell differentiation, and IL-17 production. SPH7854 can be used for the research of inflammatory bowel disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
