33984-50-8
Chemical Structure
MBD
Synonym(s): 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole
- CAS No.: 33984-50-8
- Formula:C14H12N4O4
- Molecular Weight:300.27
IUPAC Name: N-(4-methoxybenzyl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine
InChIKey: IENONFJSMWUIQQ-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC=C(NCC2=CC=C(OC)C=C2)C3=NON=C31)[O-]
Biological Activity: MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].
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MBD | 99.60% | MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule. | ||||||||||||||||||||
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- [1]. Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10(24):4433-4440. [Content Brief]
- [2]. Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141(1):128-131. [Content Brief]
Keywords
