43157-50-2
43157-50-2
Chemical Structure
2-Thioadenosine
- CAS 番号: 43157-50-2
- Formula:C10H13N5O4S
- Molecular Weight:299.31
IUPAC Name: 6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione
InChIKey: LTESOZAUMTUKQX-UUOKFMHZSA-N
SMILES: O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N(C=N2)C(N3)=C2C(N)=NC3=S
Biological Activity: 2-Thioadenosine is a selective A1 adenosine receptor (A1AR) ligand with a Ki of 80.3 nM. 2-Thioadenosine shows very low affinity for the A2A, A2B and A3 adenosine receptor subtypes. 2-Thioadenosine acts as a precursor for the synthesis of fluorescent A3 adenosine receptor-selective agonists[1].
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2-Thioadenosine | 2-Thioadenosine is a selective A1 adenosine receptor (A1AR) ligand with a Ki of 80.3 nM. 2-Thioadenosine shows very low affinity for the A2A, A2B and A3 adenosine receptor subtypes. 2-Thioadenosine acts as a precursor for the synthesis of fluorescent A3 adenosine receptor-selective agonists. | |||||||||||||||||||||
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