479-92-5
479-92-5
Chemical Structure
Propyphenazone
Synonym(s): 4-Isopropylantipyrine; Isopropylphenazone
- CAS No.: 479-92-5
- Formula:C14H18N2O
- Molecular Weight:230.31
IUPAC Name: 4-isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
InChIKey: PXWLVJLKJGVOKE-UHFFFAOYSA-N
SMILES: O=C1N(C2=CC=CC=C2)N(C)C(C)=C1C(C)C
Biological Activity: Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity[1][2].
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Propyphenazone | 99.85% | Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity. | ||||||||||||||||||||
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Propyphenazone (Standard) | ≥98% | Propyphenazone (Standard) is the analytical standard of Propyphenazone. This product is intended for research and analytical applications. Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity. | ||||||||||||||||||||
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Propyphenazone-d3 | 99.0% | Propyphenazone-d3 is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors. | ||||||||||||||||||||
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References
- [1]. F Burdan. Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol. Hum Exp Toxicol. 2004 May;23(5):235-44. [Content Brief]
- [2]. Mohamed F Radwan, et al. Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors. ACS Med Chem Lett. 2014 Jun 23;5(9):983-8. [Content Brief]
