546-88-3
Chemical Structure
Acetohydroxamic acid
Synonym(s): N-Hydroxyacetamide
- CAS No.: 546-88-3
- Formula:C2H5NO2
- Molecular Weight:75.07
IUPAC Name: N-hydroxyacetamide
InChIKey: RRUDCFGSUDOHDG-UHFFFAOYSA-N
SMILES: CC(NO)=O
Biological Activity: Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV[1][2][3].
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Acetohydroxamic acid | 99.91% | Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV. | ||||||||||||||||||||
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Acetohydroxamic acid (Standard) | ≥98% | Acetohydroxamic acid (Standard) is the analytical standard of Acetohydroxamic acid. This product is intended for research and analytical applications. Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV. | ||||||||||||||||||||
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- [1]. Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52(1):76-82. [Content Brief]
- [2]. Umamaheshwari RB, et al., Receptor-mediated targeting of lipobeads bearing acetohydroxamic acid for eradication of Helicobacter pylori. J Control Release. 2004 Sep 14;99(1):27-40. [Content Brief]
- [3]. Liu YH, et al., Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro. Drug Des Devel Ther. 2017 Jul 13;11:2139-2147. [Content Brief]