640725-74-2
Chemical Structure
2-Amino-6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine
- CAS No.: 640725-74-2
- Formula:C11H14ClN5O4
- Molecular Weight:315.71
IUPAC Name: (2R,3R,4R,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol
InChIKey: WARIDGHHZMLANX-GITKWUPZSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C=NC3=C(Cl)N=C(N)N=C32)O1
Biological Activity: 2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Amino-6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine | 2-Amino -6-chloro-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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