74925-81-8
74925-81-8
Chemical Structure
3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine
- CAS No.: 74925-81-8
- Formula:C16H21N5O6
- Molecular Weight:379.37
IUPAC Name: (2R,3S,5R)-2-(hydroxymethyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl acetate
InChIKey: BRWRDMMDQJQLQS-HBNTYKKESA-N
SMILES: OC[C@H]1O[C@@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)C[C@@H]1OC(C)=O
Biological Activity: 3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine | 3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
