76463-67-7
Chemical Structure
(RS)-AMPA monohydrate
Synonym(s): (±)-AMPA monohydrate
- CAS No.: 76463-67-7
- Formula:C7H12N2O5
- Molecular Weight:204.18
IUPAC Name: 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid hydrate
InChIKey: HFISYNCCKQHIAM-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CC1=C(C)ONC1=O.[H]O[H]
Biological Activity: (RS)-AMPA monohydrate ((±)-AMPA monohydrate) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA monohydrate does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
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(RS)-AMPA monohydrate | 99.90% | (RS)-AMPA monohydrate ((±)-AMPA monohydrate) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA monohydrate does not interfere with binding sites for kainic acid or NMDA receptors. | ||||||||||||||||||||
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- [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [Content Brief]
- [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. [Content Brief]
Keywords