76463-67-7
76463-67-7
Chemical Structure
(RS)-AMPA monohydrate
Synonym(s): (±)-AMPA monohydrate
- CAS No.: 76463-67-7
- Formula:C7H12N2O5
- Molecular Weight:204.18
IUPAC Name: 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid hydrate
InChIKey: HFISYNCCKQHIAM-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CC1=C(C)ONC1=O.[H]O[H]
Biological Activity: (RS)-AMPA monohydrate ((±)-AMPA monohydrate) is the racemate of AMPA. (RS)-AMPA monohydrate is a glutamate analogue and a potent, selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA monohydrate does not interfere with the binding sites of kainate or NMDA receptors[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(RS)-AMPA monohydrate | 99.90% | (RS)-AMPA monohydrate ((±)-AMPA monohydrate) is the racemate of AMPA. (RS)-AMPA monohydrate is a glutamate analogue and a potent, selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA monohydrate does not interfere with the binding sites of kainate or NMDA receptors. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.97
HY-100815(R)-AMPA -
Similarity Score 0.97
HY-100815A(S)-AMPA -
Similarity Score 0.97
HY-100815B(RS)-AMPA -
Similarity Score 0.96
HY-100815C(RS)-AMPA hydrobromide -
Similarity Score 0.96
HY-100815E(RS)-AMPA hydrochloride -
Similarity Score 0.83
HY-103229Cl-HIBO -
Similarity Score 0.79
HY-105476TAN 950A -
Similarity Score 0.74
HY-120243L-Ibotenic acid -
Similarity Score 0.74
HY-N2311RIbotenic acid (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [Content Brief]
- [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. [Content Brief]
