860314-33-6
Chemical Structure
Acorbine
- CAS No.: 860314-33-6
- Formula:C13H27N5O4
- Molecular Weight:317.38
InChIKey: XSJMHPOUAORGMN-UWVGGRQHSA-N
SMILES: NCCC[C@@H](C(O)=O)NC([C@H](CCCN)NC(CCN)=O)=O
Biological Activity: Acorbine is an orally active, hepatoprotective tripeptide present in the brackish-water bivalve Corbicula japonica. Hydrolysis of Acorbine yields free β-alanine and ornithine, which mediate the host defense system of Corbicula japonica in response to biological stress and changes in growth conditions. Acorbine inhibits ethanol-induced hepatocyte death and liver injury. Acorbine can be used in studies related to liver diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Acorbine | Acorbine is an orally active, hepatoprotective tripeptide present in the brackish-water bivalve Corbicula japonica. Hydrolysis of Acorbine yields free β-alanine and ornithine, which mediate the host defense system of Corbicula japonica in response to biological stress and changes in growth conditions. Acorbine inhibits ethanol-induced hepatocyte death and liver injury. Acorbine can be used in studies related to liver diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Uchisawa H, et al. A novel ornithine-containing tripeptide isolated from the extract of the brackish-water bivalve Corbicula japonica. Biochimica et biophysica acta. 2007 May;1770(5):790-6. [Content Brief]
- [2]. Tamai M, et al. Acorbine, a Corbicula japonica-derived tripeptide containing non-proteinogenic amino acids, suppresses ethanol-induced liver injury. Biochemical and biophysical research communications. 2020 Feb 12;522(3):580-584. [Content Brief]
Keywords
