88678-31-3
88678-31-3
Chemical Structure
Liranaftate
Synonym(s): Piritetrate; M-732
- CAS No.: 88678-31-3
- Formula:C18H20N2O2S
- Molecular Weight:328.43
IUPAC Name: O-(5,6,7,8-tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)(methyl)carbamothioate
InChIKey: VPHPQNGOVQYUMG-UHFFFAOYSA-N
SMILES: S=C(OC1=CC=C2CCCCC2=C1)N(C3=NC(OC)=CC=C3)C
Biological Activity: Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation[1][2][3][4].
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Liranaftate | 99.68% | Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation. | ||||||||||||||||||||
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Liranaftate (Standard) | ≥98% | Liranaftate (Standard) is the analytical standard of Liranaftate. This product is intended for research and analytical applications. Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation. | ||||||||||||||||||||
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References
- [1]. Oku, Y., et al., [Fungicidal activity of liranaftate against Trichophyton rubrum]. Nihon Ishinkin Gakkai Zasshi, 2002. 43(3): p. 181-7. [Content Brief]
- [2]. Oku, Y., N. Takahashi, and K. Yokoyama, [Fungicidal activity of liranaftate against dermatophytes]. Nihon Ishinkin Gakkai Zasshi, 2009. 50(1): p. 9-13. [Content Brief]
- [3]. Maruyama N, et, al. [Suppression of experimental inflammation by anti-fungal agent liranaftate in mice]. Nihon Ishinkin Gakkai Zasshi. 2010;51(1):7-11. [Content Brief]
- [4]. Kobayashi M, et, al. [Anti-fungal drug liranaftate suppresses fungal element-promoted production of IL-8 in normal human keratinocytes]. Nihon Ishinkin Gakkai Zasshi. 2008;49(4):319-22. [Content Brief]
Keywords
