895542-09-3
895542-09-3
Chemical Structure
Trifarotene
Synonym(s): CD5789
- CAS No.: 895542-09-3
- Formula:C29H33NO4
- Molecular Weight:459.58
IUPAC Name: 3''-(tert-butyl)-4'-(2-hydroxyethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylic acid
InChIKey: MFBCDACCJCDGBA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=CC=C(OCCO)C(C3=CC=C(N4CCCC4)C(C(C)(C)C)=C3)=C2)C=C1)O
Biological Activity: Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ～65-fold and ～16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Trifarotene | 99.12% | Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ～65-fold and ～16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively. | ||||||||||||||||||||
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Trifarotene (Standard) | ≥98% | Trifarotene (Standard) is the analytical standard of Trifarotene. This product is intended for research and analytical applications. Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively. | ||||||||||||||||||||
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Trifarotene-d4 | Trifarotene-d4 (Cd5789-d4) is the deuterium labeled Trifarotene (HY-100256). Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ～65-fold and ～16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively. | |||||||||||||||||||||
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References
