922491-46-1
922491-46-1
Chemical Structure
ACH-702
- CAS No.: 922491-46-1
- Formula:C21H25FN4O3S
- Molecular Weight:432.51
IUPAC Name: (R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cyclopropyl-6-fluoro-8-methoxyisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione
InChIKey: CECJUHKZSOSOJJ-SNVBAGLBSA-N
SMILES: O=C1NSC(N(C2=C3C=C(C(N4C[C@@H](CC4)C(N)(C)C)=C2OC)F)C5CC5)=C1C3=O
Biological Activity: ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity[1][2].
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ACH-702 | ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity. | |||||||||||||||||||||
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References
- [1]. Molina-Torres CA, et al. In vitro activity of a new isothiazoloquinolone, ACH-702, against Mycobacterium tuberculosis and other mycobacteria. Antimicrob Agents Chemother. 2010 May;54(5):2188-90. [Content Brief]
- [2]. Pucci MJ, et al. In vitro and in vivo profiles of ACH-702, an isothiazoloquinolone, against bacterial pathogens. Antimicrob Agents Chemother. 2011 Jun;55(6):2860-71. [Content Brief]
Keywords
