98907-26-7
Chemical Structure
N-Aminofluorescein
- CAS No.: 98907-26-7
- Formula:C20H14N2O4
- Molecular Weight:346.34
IUPAC Name: 2-((6-chloro-4-methylquinolin-2-yl)thio)acetic acid
InChIKey: CHYVTSCIBXXQJT-UHFFFAOYSA-N
SMILES: O=C1N(N)C2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)C5=C1C=CC=C5
Biological Activity: N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu2+ in biological systems with λex/em=495/516 nm[1][2]. N-Aminofluorescein can be used to measure the concentration of copper ions in cells[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Aminofluorescein | 99.70% | N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu2+ in biological systems with λex/em=495/516 nm. N-Aminofluorescein can be used to measure the concentration of copper ions in cells. | ||||||||||||||||||||
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References
- [1]. Chen X, et al. A selective fluorescence-on reaction of spiro form fluorescein hydrazide with Cu(II). Anal Chim Acta. 2006 Aug 11;575(2):217-22. [Content Brief]
- [2]. Uzra Diwan, et al. A water compatible turn ‘on’ optical probe for Cu2+ based on a fluorescein-sugar conjugate. Sensors and Actuators B: Chemical. 2014;196:345-351.
- [3]. Zhi HT, et al. Anticancer efficacy triggered by synergistically modulating the homeostasis of anions and iron: Design, synthesis and biological evaluation of dual-functional squaramide-hydroxamic acid conjugates. Bioorg Chem. 2024 Jun;147:107421. [Content Brief]
