Antitumor agent-127
Based on 1 Customer Validation
Antitumor agent-127 (compound 1) is a parent macrocyclic peptide. Antitumor agent-127 displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.09%
- CAS. Nr.: 3034861-58-7
- Formel: C86H107N15O18S
- Molecular Weight:1670.92
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Speicherung:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 3034861-58-7
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Appearance Solid
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Molecular Weight 1670.92
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Formel C86H107N15O18S
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Color White to off-white
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Sequence
Ac-Phe-Tyr-Leu-Val-Tyr-Ser-Gly-Trp-Tyr-{N(Me)Phe}-Leu-Cys-Gly-NH2 (thioether bridge:Phe1-Cys12)
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Sequence Shortening
Ac-FYLVYSGWY-{N(Me)Phe}-LCG-NH2 (thioether bridge:Phe1-Cys12)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (59.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (290 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5985 mL | 2.9924 mL | 5.9847 mL | 14.9618 mL |
| 5 mM | 0.1197 mL | 0.5985 mL | 1.1969 mL | 2.9924 mL | |
| 10 mM | 0.0598 mL | 0.2992 mL | 0.5985 mL | 1.4962 mL | |
| 15 mM | 0.0399 mL | 0.1995 mL | 0.3990 mL | 0.9975 mL | |
| 20 mM | 0.0299 mL | 0.1496 mL | 0.2992 mL | 0.7481 mL | |
| 25 mM | 0.0239 mL | 0.1197 mL | 0.2394 mL | 0.5985 mL | |
| 30 mM | 0.0199 mL | 0.0997 mL | 0.1995 mL | 0.4987 mL | |
| 40 mM | 0.0150 mL | 0.0748 mL | 0.1496 mL | 0.3740 mL | |
| 50 mM | 0.0120 mL | 0.0598 mL | 0.1197 mL | 0.2992 mL |
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