Carbutamide-d9
Based on 1 Customer Validation
Carbutamide-d9 (BZ-55-d9) is the deuterium labeled Carbutamide. Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1246820-50-7
- Formel: C11H8D9N3O3S
- Molecular Weight:280.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1246820-50-7
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Unlabeled Cas 339-43-5
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Molecular Weight 280.39
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Formel C11H8D9N3O3S
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SMILES
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(NS(=O)(C1=CC=C(C=C1)N)=O)=O
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Synonyms
BZ-55-d9
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kleinsorge H, et al. Carbutamide--the first oral antidiabetic. A retrospect. Exp Clin Endocrinol Diabetes. 1998;106(2):149-51. [Content Brief]
[3]. ROOT MA, et al. Pharmacology of carbutamide (p-aminophenylsulfonyl butylcarbamide). J Pharmacol Exp Ther. 1957 Apr;119(4):468-78. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)