80955-97-1
Chemical Structure
3’-Amino-3’-deoxy-5-fluorouridine
- CAS. Nr.: 80955-97-1
- Formula:C9H12FN3O5
- Molecular Weight:261.21
IUPAC Name: 1-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
InChIKey: WRNOGDJKXUHGEA-UAKXSSHOSA-N
SMILES: OC[C@@H]1[C@@H](N)[C@@H](O)[C@H](N2C(NC(C(F)=C2)=O)=O)O1
Biological Activity: 3’-Amino-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Amino-3’-deoxy-5-fluorouridine | 3’-Amino-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
