83643-88-3
Chemical Structure
(S)-AMPA
Synonym(s): L-AMPA
- CAS. Nr.: 83643-88-3
- Formula:C7H10N2O4
- Molecular Weight:186.17
IUPAC Name: (S)-2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
InChIKey: UUDAMDVQRQNNHZ-YFKPBYRVSA-N
SMILES: O=C1C(C[C@H](N)C(O)=O)=C(C)ON1
Biological Activity: (S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist[1][2].
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(S)-AMPA | 99% | (S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist. | ||||||||||||||||||||
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- [1]. J A Larm, et al. (S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors. Eur J Pharmacol. 1996 Oct 24;314(1-2):249-54. [Content Brief]
- [2]. B Ebert, et al. Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA. Neurochem Int. 1994 Jun;24(6):507-15. [Content Brief]
Keywords