DYRKs-IN-2
DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity.
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- CAS. Nr.: 1386980-04-6
- Formel: C32H38ClN9O3
- Molecular Weight:632.16
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SW-620 | EC50 |
0.18 μM
Compound: 27
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Cytotoxicity against human SW620 cells
Cytotoxicity against human SW620 cells
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[PMID: 24239188] |
DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1386980-04-6
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Molecular Weight 632.16
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Formel C32H38ClN9O3
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SMILES
O=C(C1=CC2=CN=C(NCCCN3CCN(C)CC3)N=C2NC1=O)NC4=CC(C(NC(C5=CC=CC=C5)CCN)=O)=CC=C4Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DYRKs-IN-2 Related Classifications
HY-128759 Related Classifications
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