1386980-04-6
1386980-04-6
Chemical Structure
DYRKs-IN-2
- CAS No.: 1386980-04-6
- Formula:C32H38ClN9O3
- Molecular Weight:632.16
IUPAC Name: N-(5-((3-amino-1-phenylpropyl)carbamoyl)-2-chlorophenyl)-2-((3-(4-methylpiperazin-1-yl)propyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide
InChIKey: QJRRYVISMPFJOU-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CN=C(NCCCN3CCN(C)CC3)N=C2NC1=O)NC4=CC(C(NC(C5=CC=CC=C5)CCN)=O)=CC=C4Cl
Biological Activity: DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].
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DYRKs-IN-2 | DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity. | |||||||||||||||||||||
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