1. Protein Tyrosine Kinase/RTK
  2. DYRK
  3. DYRKs-IN-2

DYRKs-IN-2 

Cat. No.: HY-128759
Handling Instructions

DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity.

For research use only. We do not sell to patients.

DYRKs-IN-2 Chemical Structure

DYRKs-IN-2 Chemical Structure

CAS No. : 1386980-04-6

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Description

DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].

IC50 & Target

IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2]

In Vitro

DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1].

Molecular Weight

632.16

Formula

C₃₂H₃₈ClN₉O₃

CAS No.

1386980-04-6

SMILES

O=C(C1=CC2=CN=C(NCCCN3CCN(C)CC3)N=C2NC1=O)NC4=CC(C(NC(C5=CC=CC=C5)CCN)=O)=CC=C4Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

DYRKs-IN-2DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseInhibitorinhibitorinhibit

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