Epimedonin L
Epimedonin L is a natural flavonoid.
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- CAS. Nr.: 2215102-38-6
- Formel: C30H34O5
- Molecular Weight:474.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI |
50 %
Compound: 7
|
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
Growth inhibition of human A549 cells at 40 uM after 48 hrs by MTS assay relative to control
|
[PMID: 29338226] |
| A549 | IC50 |
7.1 μM
Compound: 7
|
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
Cytotoxicity against human A549 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| HL-60 | IC50 |
4.3 μM
Compound: 7
|
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
Cytotoxicity against human HL60 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| MCF7 | IC50 |
5.4 μM
Compound: 7
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SMMC-7721 | IC50 |
>10 μM
Compound: 7
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
| SW480 | IC50 |
5.1 μM
Compound: 7
|
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
Cytotoxicity against human SW480 cells after 48 hrs by MTS assay
|
[PMID: 29338226] |
Epimedonin L (48 h) exhibits cytotoxic activity against human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, SW-480) (IC50 values: 4.3 μM (HL-60), 7.1 μM (A-549), 5.4 μM (MCF-7), 5.1 μM (SW-480); IC50 >10 μM (SMMC-7721))[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2215102-38-6
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Molecular Weight 474.59
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Formel C30H34O5
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SMILES
O=C1C=C(C2=CC(C/C=C(C)\C)=C(O)C(C/C=C(C)\C)=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C31
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)