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Art. -Nr.: HY-160411

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FAK-IN-18

FAK-IN-18 is a focal adhesion kinase (FAK) inhibitor with an IC₅₀ of .84 nM. FAK-IN-18 can be used for the research of gastric cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2941086-18-4
Formel: C₃₃H₃₄ClN₇O₂
Molecular Weight:596.12

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

FAK-IN-18 Chemical Structure

CAS. Nr.: 2941086-18-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

FAK-IN-18 is a focal adhesion kinase (FAK) inhibitor with an IC₅₀ of .84 nM. FAK-IN-18 can be used for the research of gastric cancer^[1].

In Vitro

FAK-IN-18 (Compound 15) inhibits SNU668 cells proliferation with an IC₅₀ of 0.11 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2941086-18-4
Molecular Weight 596.12
Formel C₃₃H₃₄ClN₇O₂
SMILES

O=C(N1CCCC(C1)C2=CC(NCC3=CC=C(NC4=NC=C(C(NC5=C(C(NC)=O)C=CC=C5)=N4)Cl)C=C3)=CC=C2)C=C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Haisheng Zhang, et al. Pyrimidine or pyridine derivative and medicinal use thereof. WO2023109751A1. 2024-06-13

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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