Dbt - dihydrolipoamide branched chain transacylase E2 Gene

Also Known as BCKAD E2; BCKAD-E2; D3Wsu60e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13171

Summary

Predicted to enable acetyltransferase activity; lipoic acid binding activity; and ubiquitin protein Ligase binding activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Used to study maple syrup urine disease. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human DBT (dihydrolipoamide branched chain transacylase E2). [provided by Alliance of Genome Resources, Apr 2022]

Dbt Products (9)

mRNA Protein Name
NM_001357344.2 NP_001344273.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 2
NM_001409891.1 NP_001396820.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 3
NM_001409892.1 NP_001396821.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 4
NM_001409893.1 NP_001396822.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 5
NM_001409894.1 NP_001396823.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 2
NM_001409895.1 NP_001396824.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 2
NM_001409896.1 NP_001396825.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 6
NM_001409897.1 NP_001396826.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 2
NM_010022.5 NP_034152.2 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 1
Protein Preferred Names Protein Names

lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

  • branched-chain alpha-keto acid dehydrogenase complex component E2

  • branched-chain alpha-ketoacid dehydrogenase, E2 subunit

  • dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex

  • dihydrolipoyl transacylase

  • d

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-109195 Vebicorvir Inhibitor 99.43% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-B0973 Dibenzothiophene Inhibitor 99.92% Unkown
HY-156746 DBt-10 Degrader / Unkown
HY-RS03554 DBT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17320 Dbt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23775 Dbt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dbt NCBI NCBI:1629